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2-Chloro-5-trifluoromethylpyridine

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The export volume of pesticides in China has reached as high as 2.05 million tons, hitting a new historical high!

The export volume of pesticides in China has reached as high as 2.05 million tons, hitting a new historical high!

Statistics of China’s pesticide export in the past two years

Statistics of China’s pesticide export in the past two years

Current situation and achievements of pesticide trade in China

Current situation and achievements of pesticide trade in China

Innovative Chemical Compound: 2-Chloro-5-chloromethylpyridine (CCMP)

Innovative Chemical Compound: 2-Chloro-5-chloromethylpyridine (CCMP)

Shandong Jihui Chemical Co., LTD : Deep cultivation of fine chemical industry, cast a diversified industrial pattern.

Shandong Jihui Chemical Co., LTD : Deep cultivation of fine chemical industry, cast a diversified industrial pattern.

Fluazinam

2-Hydroxy-6-trifluoromethylpyridine

2-Hydroxy-6-trifluoromethylpyridine

2-Amino-5-methylpyridine

2-Amino-5-methylpyridine

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine

N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine

4.4′-Bis(chloromethyl)biphenyl

4.4′-Bis(chloromethyl)biphenyl

2-Hydroxy-3-trifluoromethylpyridine

2-Hydroxy-3-trifluoromethylpyridine

2,3-Dichloro-5-trifluoromethylpyridine

2,3-Dichloro-5-trifluoromethylpyridine

2-Fluoro-5-trifluoromethylpyridine

2-Fluoro-5-trifluoromethylpyridine

3-Trifuoromethylcinnamic acid

3-Trifuoromethylcinnamic acid

2,6-Dichloroaniline

2,6-Dichloroaniline

(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

Picoxystrobin

methyl 4-chloropicolinate

methyl 4-chloropicolinate

N-Methyl-4-chloro-2-pyridinecarboxamide

N-Methyl-4-chloro-2-pyridinecarboxamide

2-Chloro-5-trifluoromethylpyridine

2-Chloro-5-trifluoromethylpyridine

2-Chloro-5-trifluoromethylpyridine

CAS: 52334-81-3

Molecular Formula: C6H3ClF3N

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Description

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2-Chloro-5-trifluoromethylpyridine – Introduction

52334-81-3 – Names and Identifiers

Name	2-Chloro-5-trifluoromethylpyridine
Synonyms	5-CTF 2,5-CTF oro-5-(trifL 2 – chloro – 5-3 Methyl pyridine 2-Chloro-5-trifluoromethylpyridine 2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE 2-Chloro-5-(trifluoromethyl)pyridine 2-chloro-5-(trifluoromethyl)-pyridin 2-chlorine-5-trifluoromethyl pyridine
CAS	52334-81-3
EINECS	257-856-5
InChI	InChI=1/C6H3ClF3N/c7-5-2-1-4(3-11-5)6(8,9)10/h1-3H
InChIKey	JFZJMSDDOOAOIV-UHFFFAOYSA-N

52334-81-3 – Physico-chemical Properties

Molecular Formula	C6H3ClF3N
Molar Mass	181.54
Density	1.417g/mLat 25°C(lit.)
Melting Point	32-34°C(lit.)
Boling Point	152 °C
Flash Point	>230°F
Appearance	Crystalline Low Melting Solid
Specific Gravity	1.417
Color	White to yellow
BRN	3649688
pKa	-2.57±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
MDL	MFCD00042225
Physical and Chemical Properties	Density 1.417 melting point 29-33°C boiling point 152°C flash point 65°C
Use	Used as a pesticide intermediate

52334-81-3 – Risk and Safety

Risk Codes	R36/37/38 – Irritating to eyes, respiratory system and skin. R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R25 – Toxic if swallowed R11 – Highly Flammable
Safety Description	S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 – Wear suitable gloves and eye/face protection S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S22 – Do not breathe dust. S16 – Keep away from sources of ignition.
UN IDs	2811
WGK Germany	3
RTECS	US7530000
TSCA	T
HS Code	29339900
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	III

52334-81-3 – Reference Information

EPA chemical information	Information provided by: ofmpub.epa.gov (external link)
Use	2-chloro-5-trifluoromethylpyridine is an intermediate of the herbicides pyrifluoxaline and flupirchloroxaline, It is also an intermediate of the insecticide fluazinourea. The intermediate of the herbicide pyrifluoxazole. At present, fluorine-containing pesticide intermediates are in urgent need of vigorous development. In addition to this product, 2-hydroxy-3-chloro-trifluoromethylphenol, p-chlorotrifluorotoluene, 3 ‘,3′-trifluoro-2’-chloropropene, 3-phenoxy-4-fluorobenzaldehyde are important varieties. Used as pesticide intermediate pesticide intermediate; pharmaceutical intermediate; liquid crystal material intermediate
Production method	It is obtained by fluorination of 2-chloro-5-trichloromethylpyridine. The preparation method is based on 3-methylpyridine as the raw material, first chlorinated to obtain 2-chloro-5-trichloromethylpyridine, and then further fluorinated to obtain the product; also can use 3-methylpyridine As a raw material, the product is obtained by performing a chlorofluorination reaction in the presence of a catalyst. You can also use 2-chloro-5-methylpyridine as a raw material, use chlorine to first chlorinate the side chain to 2-chloro-5-trichloromethylpyridine, and then use hydrogen fluoride to obtain the product. See the reaction formula:

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