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N-Methyl-4-chloro-2-pyridinecarboxamide
CAS: 220000-87-3;338992-20-4
Molecular Formula: C7H7ClN2O
Description
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N-Methyl-4-chloro-2-pyridinecarboxamide- Introduction
220000-87-3 – Names and Identifiers
|
Name |
N-Methyl-4-chloro-2-pyridinecarboxamide |
|
Synonyms |
IFLAB-BB F2108-0189 |
|
CAS |
|
|
EINECS |
606-888-1 |
|
InChI |
InChI=1/C7H7ClN2O/c8-5-1-2-10-6(3-5)4-7(9)11/h1-3H,4H2,(H2,9,11) |
220000-87-3 – Physico-chemical Properties
|
Molecular Formula |
|
|
Molar Mass |
170.6 |
|
Density |
1.264±0.06 g/cm3(Predicted) |
|
Melting Point |
41-43°C |
|
Boling Point |
317.8±27.0 °C(Predicted) |
|
Flash Point |
166.914°C |
|
Solubility |
Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met |
|
Vapor Presure |
0mmHg at 25°C |
|
Appearance |
Light-yellow solid |
|
Color |
Off-White to Light Yellow Low-Melting |
|
pKa |
13.41±0.46(Predicted) |
|
Storage Condition |
Keep in dark place,Sealed in dry,Room Temperature |
|
Refractive Index |
1.575 |
|
MDL |
MFCD02185921 |
220000-87-3 – Risk and Safety
|
Hazard Symbols |
Xn – Harmful |
|
Risk Codes |
R22 – Harmful if swallowed |
|
Safety Description |
26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
220000-87-3 – Reference Information
|
introduction |
N-methyl -4-chloro -2-picolinamide is a white powdery substance, which is an intermediate of sorafenib, a clinical anticancer drug for the treatment of liver and renal cell carcinoma; Sorafenib intermediate. |
|
application |
N-methyl -4-chloro -2-pyridine formamide can be used as an intermediate in organic synthesis and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical synthesis process. |
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