N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine

CAS: 444731-75-3

Molecular Formula: C14H14ClN5

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Description

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N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine-Introduction

444731-75-3 – Names and Identifiers

Name	N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine
Synonyms	BNKY007-PZ02 Pazopanib Impurity 22 N-(2-chloropyrimidin-4-yl)-N,2,3-trimethylindazol-6-amine 2H-Indazol-6-aMine, N-(2-chloro-4-pyriMidinyl)-N,2,3-triMethyl- 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazol-6-amine
CAS	444731-75-3
EINECS	810-050-2
InChI	InChI=1/C14H14ClN5/c1-9-11-5-4-10(8-12(11)18-20(9)3)19(2)13-6-7-16-14(15)17-13/h4-8H,1-3H3

444731-75-3 – Physico-chemical Properties

Molecular Formula	C14H14ClN5
Molar Mass	287.75
Density	1.33±0.1 g/cm3(Predicted)
Melting Point	167-173℃
Boling Point	524.4±35.0 °C(Predicted)
Flash Point	270.976°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
Vapor Presure	0mmHg at 25°C
pKa	2.82±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Stability	Hygroscopic
Refractive Index	1.673

444731-75-3 – Introduction

N-(2-choropyrimidin-4-yl)-N,2, is a chemical substance that has the following properties:

Nature:
-Appearance: usually white to light yellow crystal or crystalline powder
-Molecular formula: C14H14ClN5
-Molecular Weight: 291.75
-melting point:>300 ℃
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide, dichloromethane

Use:
N-(2-chloropyrimidin-4-yl)-N,2, can be used to prepare organic fluorescent dyes with fluorescent properties, and can also be used as intermediates in organic synthesis. Due to its special structure, it has important application potential in some medical fields and materials science.

Preparation Method:
N-(2-chloropyrimidin-4-yl)-N,2, the preparation method of Cr can be completed by chemical synthesis. A common synthetic method is to use N-methyl -2,3-dimethyl -2H-indazol-6-amine as the starting material and carry out nucleophilic substitution reaction with 2-chloropyrimidin-4-one to produce the desired product.

Safety Information:
Regarding the specific safety information of N-(2-chloropyrimidin-4-yl)-N,2, it needs to be strictly controlled and managed during use, storage and transportation. It may be toxic and irritating to the human body and should avoid contact with the skin, inhalation or ingestion. Wear appropriate personal protective equipment and follow proper laboratory practices to ensure personal safety and environmental protection. Consult the relevant safety data forms when handling the substance and follow the appropriate safety procedures.